Synthesis, Anticancer Activity and Molecular Docking Study of some New Thiazolo[2, 3-a]Pyrimidinedione-Based Heterocyclic Compounds
نویسندگان
چکیده
منابع مشابه
Synthesis of Some New Heterocyclic Compounds with Potential Biological Activity
A series of new 2-arylimino-3-aryl-5-[5?-(3,4-dichlorophenyl)-2?-furylidene]-4-thiazolidinones (3a-l) have been synthesised by the condensation of 5-(3,4-dichlorophenyl)-2-furaldehyde 1 with 2-arylimino-3-aryl-5H-4-thiazolidinones 2 in glacial acetic acid. The physical and spectral data of the synthesised compounds are determined. The synthesised compounds have been screened for their in vitro ...
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a series of new 2-arylimino-3-aryl-5-[5?-(3,4-dichlorophenyl)-2?-furylidene]-4-thiazolidinones (3a-l) have been synthesised by the condensation of 5-(3,4-dichlorophenyl)-2-furaldehyde 1 with 2-arylimino-3-aryl-5h-4-thiazolidinones 2 in glacial acetic acid. the physical and spectral data of the synthesised compounds are determined. the synthesised compounds have been screened for their in vitro ...
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Synthesis, Evaluation of Anticancer Activity and QSAR Study of Heterocyclic Esters of Caffeic Acid
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Caffeic acid phenethyl ester(CAPE) suppresses the growth of transformed cells such as human breast cancer cells, hepatocarcinoma , myeloid leukemia, colorectal cancer cells, fibrosarcoma, glioma and melanoma. A group of heterocyclic esters of caffeic acid was synthesized using Mitsunobu reaction and the esters were subjected to further structural modification by electrooxidation of the catecho...
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ژورنال
عنوان ژورنال: Egyptian Journal of Chemistry
سال: 2023
ISSN: ['0449-2285', '2357-0245']
DOI: https://doi.org/10.21608/ejchem.2023.188464.7479